chem 348 reagents – Flashcards
Unlock all answers in this set
Unlock answersquestion
CH2I2, Zn (Cu) Et2O2 |
answer
Simmons Smith (alkene->Carbene) |
question
O3 CH2Cl2 -78 |
answer
Ozonolysis (alkene-> aldehyde) |
question
KMnO4 |
answer
Oxidative Cleavage (Alkene-> carboxylic acids) |
question
? |
answer
Cyclopropanation |
question
OsO4 NaIO4 THF or tBuOH when using KMnO4: |
answer
Periodate cleavage (alkene to ald/ketone) KMno4= carboxyic acids |
question
HgSO4 H2SO4 |
answer
Hydration of Alkynes (alkyne to carboxylic acid or ketone) |
question
NBS hv CCl4 |
answer
Allylic or Benzylic Bromination (addition of bromine to allylic or benzylic carbon) |
question
1.) 9 BBN 2.) H2o2, NaOH |
answer
Hydration of Alkynes (alkyne to Aldehyde) |
question
1.) Hg(OAc)2, H20 2.) NaBH4 |
answer
oxymercuration reduction (alkene to OH on markovnikov carbon) |
question
1.) BH3 THF 2.) NAOH H2O2 |
answer
Hydroboration oxidation (alkene to OH on antimarkovnikov carbon) |
question
-:CH2 |
answer
Carbene formation (alkene to carbene) |
question
H2N NH2 KOH |
answer
Wolff Kishner RXN Ketone taken off |
question
1. CH3-NH2, H+, -H2O 2. NaBH4/MeOH |
answer
Reductive amination (Ketone->Imine-> Amine) |
question
Starting w/ Benzene: 1.) HNO3 2.) SNCl2/HCL MeOH 3.) NaNO2/H2SO4 |
answer
formation of diazonium ion N triple bond N good LG |
question
Diazonium + CuCl |
answer
chlorbenzene |
question
Diazonium + CuBr |
answer
bromobenzene |
question
Diazonium + NaI |
answer
Iodine-benzene |
question
Diazonium + H3PO2 |
answer
Benzene |
question
Diazonium + phenol and NaOH |
answer
azo dye |
question
Diazonium + Ch3OH |
answer
Reflux benzene-OCH3 |
question
Diazonium + H20, 100 C OR Cu2O, Cu(NO3)2 |
answer
phenol |
question
Diazonium + CuCn |
answer
benzene w/ nitrile |
question
t-butyl benzene + H2CrO4, H2SO4/H2O, heat |
answer
side chain oxidation (benzene disapears, carboxylic acid w/t-butyl on it) |
question
Na2CrO7, H2O2, Aceton |
answer
Jones Oxidation secondary alcohol to Ketone |
question
1.DMSO, (COCl)2 CH2Cl2 -60 2.Et3N -20 |
answer
Swern Oxidation primary alcohol to aldehyde |
question
periodinane -HOAc |
answer
Primary alchol to aldehyde |
question
LDA, THF, -78C |
answer
product of kinetic enolate |
question
Ph3P=CHCH2Ch3 +aldehyde or ketone |
answer
wittig (carbonyl to alkene) |
question
1.) NaH, THF b.) PhCHO |
answer
Emmons-horner reaction (carbonyl to alkene) |
question
NaCN, H+ aldeh/ketone |
answer
formation of cyanohydrin |
question
TMSCN |
answer
cyanohydrin protecting group |
question
ketone + HONH3CL, py or NaOAC |
answer
oxime formation |
question
oxime+ PCl5 or H2SO4 |
answer
Beckmann Rearrangement |
question
CN DIBAL (1eq) |
answer
Reduction to CHO |
question
CN DIBAL (2eq) |
answer
Reduction to NH2 |
question
CO2H DIBAL (2eq) |
answer
Reduction to CHO |
question
Ester DIBAL (1eq) |
answer
Reduction to CHO |
question
Br2, HOAc + carbonyl |
answer
alpha halogenation |
question
ketone + mcpba |
answer
ester |