Final Exam

Glomerular Filtration Rate (GFR)
Best clinical estimate of functioning renal mass
Clearance
Amount filtered: actually “cleared” from blood
Units of clearance
ml/min
Iothalamate
radiolabeled; expensive; limited practical use
Inulin
polysaccharide
Problems with creatinine clearance
Proximal tubular secretion of creat
Creatinine Clearance normal
100+/- 25
Normal Values for Plasma Creatinine
0.6-1.2
Creatinine prodxn
depends on muscle mass