penicillins differ in their: 1.chemical stability in stomach acid 2.susceptibility to penicillinase 3.spectrum of action,i.e.,narrow or extended 4.route of administration 5. duration of action 6. site of action
penicillins are also called beta-lactams, which is a term relating to their agents with a similar chemical structure. theu are all virtually bactericidal agents with a similar chemical structure,and therefore a similar mechanism of action.
clients recieving penicillins 1.take a careful medication history before administering penicillins. 2.observe the client for indications of allergic reaction,including rash,fever,chills,and anaphylaxis. 3.oral penicillins should be given 1-2 hrs before or 2-3hrs after meals. 4.injection sites must be checked carefully for signs of local reactions(e.g,redness,phlebitis).Do not use the same needle for withdrawing the solution from the vial and administering it. 5. never give procaine penicillin intravenously.