
50 + (2.3 x Height in Inches over 60)
45 + (2.3 x Height in Inches over 60) 


ABW=IBW + 0.4 (TBW – IBW) 


square root of ht(cm)x Wt(kg)/3,600 

what equation is used to calculate the CrCl ml/min? 

CockcroftGault equation
(140age)(Wt Kg)/(72)(SrCr mg/dl) 

What are the normal values for CrCl in men and women 

Normal CrCl 97137 ml/min males 88128 ml/min females Renal dysfunction <60ml/min 

What is the normal creatinine levels in men and women 

Normal creatinine in men 0.8 to 1.3 mg/dl and in women: 0.6 to 1.0 mg/dl. 

What is the Volume of Distribution equation 


The elimination rate constant equation 



t ? hr= 0.693/Kd Or t ? hr= (0.693)(Vd)/Cl 

What is the SS Steady State? 

Point at which, after multiple doses, amount of drug administered over a dosing interval equals amount of drug being eliminated over that same period 

Which body weight should you use to calculate CrCl 

IBW unless the person is OBESE, then use the adjusted body weight 

what’s the criteria for being obese 

if your actual body weight is 20% greater than your IBW 

What can you say about a drug that has a high Vd(L) 


What can you say about a drug that has a low Vd(L) 


if you double the dose and the concentration doubles, what order drug is it? 



The fraction of the drug eliminated is constant 

Describe Zero order drugs 

The AMOUNT of Drug eliminated over time is constant 

What is CrCl and indicator of? 

of how well your kidneys are working 
